Research Use Only — Not for Human Consumption. This compound is sold exclusively for in vitro laboratory research by qualified professionals.
KPV
KPV — Alpha-MSH C-Terminal Tripeptide
KPV is a tripeptide corresponding to the C-terminal sequence of alpha-MSH (αMSH[11-13]). It retains significant anti-inflammatory potency despite its small size, operating through MC1R and MC3R-mediated pathways as well as receptor-independent mechanisms. Research has characterized its protective effects on intestinal epithelial cells, its ability to suppress NF-κB activation, and its modulation of inflammatory cytokine production (TNF-α, IL-1β, IL-6). Its stability and oral activity in some models make it particularly useful for GI inflammation research. For research use only — not for human consumption.
Third-Party Tested. Every Lot.
Every batch of KPV undergoes independent HPLC and mass spectrometry analysis through an accredited third-party laboratory before it is released for sale. No exceptions. No internal-only certificates.
RP-HPLC Analysis
Every lot measured by reverse-phase HPLC. KPV consistently achieves 99.3%+ purity across batches.
ESI Mass Spec
Electrospray ionization mass spectrometry confirms exact molecular weight and rules out structural isomers or impurities.
Lot-Specific CoA
Your Certificate of Analysis references your exact lot number with actual chromatogram data — not a generic template.
Theoretical Research Analysis
All research information below reflects published preclinical literature only. This product is not for human use, consumption, or clinical application of any kind.
KPV is notable for its anti-inflammatory potency relative to its small size. The minimal three-residue sequence retains the activity of the full αMSH C-terminus, making it an attractive probe for studying melanocortin anti-inflammatory mechanisms.
Sequence Information
Amino acid sequence:
Lys-Pro-ValMolecular Formula
C₁₆H₃₁N₅O₄
Molecular Weight
357.45 g/mol
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