Research Use Only — Not for Human Consumption. This compound is sold exclusively for in vitro laboratory research by qualified professionals.
5-Amino-1MQ
5-Amino-1-Methylquinolinium — NNMT Inhibitor
5-Amino-1-methylquinolinium (5-Amino-1MQ) is a quaternary amine compound that inhibits NNMT, an enzyme responsible for methylating nicotinamide and producing 1-methylnicotinamide. NNMT overexpression in adipose tissue has been associated with obesity-related metabolic dysfunction, as it depletes S-adenosylmethionine (SAM) and reduces NAD+ pools. NNMT inhibition with 5-Amino-1MQ restores SAM availability, increases NAD+ levels, and activates SIRT1 signaling in cell models. For research use only — not for human consumption.
Third-Party Tested. Every Lot.
Every batch of 5-Amino-1MQ undergoes independent HPLC and mass spectrometry analysis through an accredited third-party laboratory before it is released for sale. No exceptions. No internal-only certificates.
RP-HPLC Analysis
Every lot measured by reverse-phase HPLC. 5-Amino-1MQ consistently achieves 99.2%+ purity across batches.
ESI Mass Spec
Electrospray ionization mass spectrometry confirms exact molecular weight and rules out structural isomers or impurities.
Lot-Specific CoA
Your Certificate of Analysis references your exact lot number with actual chromatogram data — not a generic template.
Theoretical Research Analysis
All research information below reflects published preclinical literature only. This product is not for human use, consumption, or clinical application of any kind.
NNMT inhibition has emerged as a promising strategy in metabolic research for restoring NAD+ bioavailability and SAM-dependent methylation. 5-Amino-1MQ is the most commonly used tool compound for NNMT inhibition studies in cell and animal models.
Sequence Information
Amino acid sequence:
N/A — small moleculeMolecular Formula
C₁₀H₁₁ClN₂
Molecular Weight
194.66 g/mol
You May Also Like
View allAOD-9604
AOD-9604 — hGH Fragment 177–191
L-Glutathione
L-Glutathione Reduced — 1500 mg
MOTS-C
MOTS-C — Mitochondrial-Derived Peptide
SS-31
SS-31 (Elamipretide) — Mitochondria-Targeted Peptide