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Research Use Only — Not for Human Consumption. This compound is sold exclusively for in vitro laboratory research by qualified professionals.

PeptaPeptides
MOTS-C
10 mg
99.2% PurityFor Research Use Only
RUO — Research Use Only
Not for human, veterinary, or clinical use
RUO
MetabolicNew

MOTS-C

MOTS-C — Mitochondrial-Derived Peptide

(95 reviews)
99.2% Purity
$119.99per 10 mg · lyophilized

MOTS-C (Mitochondrial-derived peptide from the 12S rRNA Open reading frame of Type 2) is a 16-amino acid peptide encoded within the mitochondrial genome and secreted in response to metabolic stress. It translocates to the nucleus and activates AMPK-mediated pathways that regulate glucose uptake, fatty acid oxidation, and mitochondrial function. Research has demonstrated its ability to improve insulin sensitivity in rodent models and protect against age-related metabolic decline. For research use only — not for human consumption.

3rd-Party HPLC Verified
Lot-Specific Certificate
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Chemical Information
Molecular FormulaC₇₀H₁₁₁N₁₉O₂₀S
Molecular Weight1574.81 g/mol
CAS Number1448543-79-0
FormLyophilized Powder
Storage-20°C, dry & dark
Purity (HPLC)≥ 99.2%
Amino Acid SequenceMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
1
17 in stock
Not for Human Consumption · For Research Purposes Only
256-bit SSL
Cold-Chain Shipping
Lot-Specific CoA
ISO 9001 Facility
Independent Verification

Third-Party Tested. Every Lot.

Every batch of MOTS-C undergoes independent HPLC and mass spectrometry analysis through an accredited third-party laboratory before it is released for sale. No exceptions. No internal-only certificates.

RP-HPLC Analysis

Every lot measured by reverse-phase HPLC. MOTS-C consistently achieves 99.2%+ purity across batches.

ESI Mass Spec

Electrospray ionization mass spectrometry confirms exact molecular weight and rules out structural isomers or impurities.

Lot-Specific CoA

Your Certificate of Analysis references your exact lot number with actual chromatogram data — not a generic template.

Research Context

Theoretical Research Analysis

All research information below reflects published preclinical literature only. This product is not for human use, consumption, or clinical application of any kind.

Mitochondrial-derived peptide biology
AMPK activation and insulin sensitization
Mitochondrial biogenesis and function
Age-related metabolic decline models
Nuclear AMPK pathway research

MOTS-C represents a novel class of mitochondria-encoded bioactive peptides, challenging the paradigm that mitochondria serve purely as energy organelles. Its translation from mitochondrial to nuclear signaling function has generated significant interest in the geroscience and metabolic biology communities.

Sequence Information

Amino acid sequence:

Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular Formula

C₇₀H₁₁₁N₁₉O₂₀S

Molecular Weight

1574.81 g/mol

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FDA Disclaimer: The information and statements contained on this website have not been evaluated by the United States Food and Drug Administration. The products offered by PeptaPeptides LLC and the statements made herein are not intended to diagnose, treat, cure, or prevent any disease or medical condition. PeptaPeptides LLC functions solely as a chemical supplier and raw material provider. PeptaPeptides LLC is not a compounding pharmacy, nor does it constitute a chemical compounding facility as that term is defined under Section 503A of the Federal Food, Drug, and Cosmetic Act. PeptaPeptides LLC is likewise not an outsourcing facility as defined under Section 503B of the Federal Food, Drug, and Cosmetic Act. All compounds and materials offered are provided exclusively for laboratory research, scientific analysis, and in vitro use by qualified researchers and institutions. None of the products available through PeptaPeptides LLC are intended for, approved for, or suitable for human consumption in any form.