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Research Use Only — Not for Human Consumption. This compound is sold exclusively for in vitro laboratory research by qualified professionals.

PeptaPeptides
LL-37
5 mg
99.0% PurityFor Research Use Only
RUO — Research Use Only
Not for human, veterinary, or clinical use
RUO
Cytoprotective

LL-37

LL-37 — Human Cathelicidin Antimicrobial Peptide (5 mg)

(112 reviews)
99.0% Purity
$129.99per 5 mg · lyophilized

LL-37 is the sole human cathelicidin, processed from the precursor hCAP-18 by proteinase 3 cleavage. It adopts an amphipathic α-helical structure that disrupts bacterial membranes and interacts with pattern recognition receptors to modulate innate immune signaling. Beyond its antimicrobial role, LL-37 activates FPR2/ALX receptors, modulates TLR signaling, promotes angiogenesis, and stimulates keratinocyte migration and proliferation. Its multifunctional profile makes it valuable across infection biology, immunology, and wound healing research. For research use only — not for human consumption.

3rd-Party HPLC Verified
Lot-Specific Certificate
Cold-Chain Shipping
Chemical Information
Molecular FormulaC₂₀₅H₃₄₁N₆₁O₅₃S₁
Molecular Weight4493.32 g/mol
CAS Number154947-66-7
FormLyophilized Powder
Storage-20°C, dry & dark
Purity (HPLC)≥ 99.0%
Amino Acid SequenceLeu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
1
12 in stock — limited
Not for Human Consumption · For Research Purposes Only
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Cold-Chain Shipping
Lot-Specific CoA
ISO 9001 Facility
Independent Verification

Third-Party Tested. Every Lot.

Every batch of LL-37 undergoes independent HPLC and mass spectrometry analysis through an accredited third-party laboratory before it is released for sale. No exceptions. No internal-only certificates.

RP-HPLC Analysis

Every lot measured by reverse-phase HPLC. LL-37 consistently achieves 99.0%+ purity across batches.

ESI Mass Spec

Electrospray ionization mass spectrometry confirms exact molecular weight and rules out structural isomers or impurities.

Lot-Specific CoA

Your Certificate of Analysis references your exact lot number with actual chromatogram data — not a generic template.

Research Context

Theoretical Research Analysis

All research information below reflects published preclinical literature only. This product is not for human use, consumption, or clinical application of any kind.

Antimicrobial mechanism studies
Innate immune signaling and TLR modulation
Keratinocyte migration and wound healing
Angiogenesis and vascular biology
FPR2/ALX receptor pharmacology

LL-37 occupies a unique position in innate immunity research as the only human cathelicidin. Its dual role as both a direct antimicrobial agent and an immunomodulatory signaling molecule makes it a high-value tool across multiple research disciplines.

Sequence Information

Amino acid sequence:

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser

Molecular Formula

C₂₀₅H₃₄₁N₆₁O₅₃S₁

Molecular Weight

4493.32 g/mol

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FDA Disclaimer: The information and statements contained on this website have not been evaluated by the United States Food and Drug Administration. The products offered by PeptaPeptides LLC and the statements made herein are not intended to diagnose, treat, cure, or prevent any disease or medical condition. PeptaPeptides LLC functions solely as a chemical supplier and raw material provider. PeptaPeptides LLC is not a compounding pharmacy, nor does it constitute a chemical compounding facility as that term is defined under Section 503A of the Federal Food, Drug, and Cosmetic Act. PeptaPeptides LLC is likewise not an outsourcing facility as defined under Section 503B of the Federal Food, Drug, and Cosmetic Act. All compounds and materials offered are provided exclusively for laboratory research, scientific analysis, and in vitro use by qualified researchers and institutions. None of the products available through PeptaPeptides LLC are intended for, approved for, or suitable for human consumption in any form.